Nicotinamide riboside is a nicotinic acid that has been shown to combat nicotinamide adenine dinucleotide (NAD) depletion. NAD, also known as co-enzyme two or nicotinamide adenine dinucleotide phosphate (NADP), is an essential enzyme in metabolism and plays a role in producing ATP energy for cells. Nicotinamide riboside before and after studies show that it can inhibit the breakdown of NAD+ by nicotinamidase enzymes, which reduces oxidative stress. In addition to its effect on cell health, nicotinamide riboside may spur other metabolic processes such as lipolysis (breakdown of fat).
Does nicotinamide riboside works?
In a test tube, nicotinamide riboside (a vitamin) was used on cells from a person with Parkinson’s Disease. The cells became better and had higher levels of NAD+. It is not clear yet if this will help people with age-related brain disorders. More studies need to be done.
Check online for more studies and papers on this subject.